Biochemical Markers as Evidence of the Effects of Environmental Enrichment on Physiological Processes in Huntington’s Disease Patients

The University does not authorize you to copy, communicate or otherwise make available electronically to any other person any copyright material contained on this site. You are reminded of the following:  Copyright owners are entitled to take legal action against persons who infringe their copyright.  A reproduction of material that is protected by copyright may be a copyright infringement.  A court may impose penalties and award damages in relation to offences and infringements relating to copyright material. Higher penalties may apply, and higher damages may be awarded, for offences and infringements involving the conversion of material into digital or electronic form. ii Acknowledgements I would like to thank Associate Professor, Mel Ziman and Dr. Jennifer Thompson, both admirable scientists, for their invaluable guidance, assistance, encouragement and patience throughout the entirety of my project. It has been a privilege to have had the opportunity to work with scientists of such high calibre. I would also like to thank Anna Reid, Alvaro Reyes and Travis Cruickshank for their assistance throughout the year and to extend my appreciation to the staff and members of the Faculty of Medical Sciences at ECU for providing support throughout the year. I would like to thank all the Huntington's patients and their carers in the study for their cooperation and involvement in this project. Finally, I would like to thank my family for their support and encouragement this year. I certify that this thesis does not, to the best of my knowledge and belief: (i) incorporate without acknowledgment any material previously submitted for a degree or diploma in any institution of higher education; (ii) contain any material previously published or written by another person except where due reference is made in the text; or (iii) contain any defamatory material